- Liz Highleyman | 11 December 2015
Merck's
grazoprevir/elbasvir combination cured 93% of people with HIV and hepatitis C
co-infection, was well-tolerated and did not appear to interact with
antiretrovirals, according to final results from the C-EDGE Co-infection study
presented at ...
- Keith Alcorn | 09 December 2015
The cost of treating hepatitis C (HCV) is likely to decline
dramatically over the next decade in the United States, not because of cuts in
drug prices but because the population in ...
- Liz Highleyman | 07 December 2015
Drinking
coffee was associated with lower liver stiffness – a non-invasive measure used
to estimate liver fibrosis – in people with hepatitis B, hepatitis C and
non-alcoholic fatty liver disease (NAFLD), researchers reported ...
- Liz Highleyman | 30 November 2015
People
with hepatitis C who did not achieve sustained virological response with a
prior short course of direct-acting antiviral (DAA) therapy had a high
likelihood of being cured if treated again with sofosbuvir/ledipasvir ...
- Liz Highleyman | 26 November 2015
Response-guided
therapy using an all-oral regimen of three direct-acting antivirals cured a
majority of easier-to-treat genotype 1b hepatitis C patients in just 3 weeks,
according to results from the small SODAPI pilot study, ...
- Michael Carter | 25 November 2015
The number of hepatitis C virus (HCV)-related referrals for liver transplant
has declined significantly since the introduction of HCV direct-acting
antivirals (DAAs), according to two US studies presented to the recent 2015 ...
- Michael Carter | 24 November 2015
A large proportion
of patients with chronic hepatitis C virus (HCV) infection in the UK have
co-morbidities, hazardous use of drugs and alcohol and are taking medications
that can potentially interact with HCV ...
- Liz Highleyman | 23 November 2015
A majority of people
with chronic hepatitis C and advanced fibrosis or cirrhosis showed improvement
in liver health following treatment, according to study findings presented last week at the 2015 AASLD Liver ...
- Liz Highleyman | 20 November 2015
An
all-oral combination of daclatasvir, sofosbuvir and ribavirin taken for 12 or
16 weeks led to high sustained virological response rates for people with
hard-to-treat hepatitis C virus (HCV) genotype 3 and advanced ...
- Liz Highleyman | 20 November 2015
Interferon-free
treatment with daclatasvir plus sofosbuvir, with or without ribavirin, led to
sustained virological response in a majority of people with genotype 3
hepatitis C virus (HCV) and advanced liver disease treated in ...
- Liz Highleyman | 20 November 2015
Women with chronic hepatitis B and high viral
load who were treated with tenofovir (Viread)
during pregnancy were significantly less likely to transmit hepatitis B virus
(HBV) to their babies, according to study ...
- Keith Alcorn | 18 November 2015
A combination of two experimental direct-acting antivirals developed
by AbbVie cured 93 to 97% of people with genotype 3 hepatitis C infection after
a 12-week course of treatment, Paul Kwo of Indiana ...
- Liz Highleyman | 18 November 2015
A triple combination of Gilead Sciences'
sofosbuvir/ledipasvir (Harvoni) plus
the experimental HCV protease inhibitor vedroprevir cured 96% of
treatment-experienced, genotype 1 hepatitis C patients with cirrhosis, without the
need for ribavirin, according to study ...
- Liz Highleyman | 17 November 2015
A co-formulation of sofosbuvir and the pan-genotypic HCV NS5A inhibitor
velpatasvir from Gilead Sciences produced sustained
response in 99% of people with hepatitis C virus genotypes 1, 2, 4, 5 and 6, ...
- Keith Alcorn | 17 November 2015
Re-treating with an interferon-free regimen that previously
failed to cure hepatitis C can result in success if treatment is intensified
with the addition of sofosbuvir, two studies presented at the 2015 AASLD ...
- Keith Alcorn | 17 November 2015
Around one in six people with hepatitis C in four US states
had their prescriptions for direct-acting antivirals refused by insurers, and
almost half of Medicaid recipients were denied reimbursement in 2014 ...
- Keith Alcorn | 16 November 2015
A combination of two experimental direct-acting antivirals
developed by AbbVie cured 97 to 100% of non-cirrhotic people with genotype 1
hepatitis C infection in a mid-stage phase 2 study presented this week ...
- Liz Highleyman | 16 November 2015
The nucleic acid-based polymer REP 2139, used first as
monotherapy then combined with pegylated interferon, reduced hepatitis B
surface antigen (HBsAg) levels, lowered hepatitis delta viral load and
increased anti-HBs antibody titres, according ...
- Keith Alcorn | 16 November 2015
The burden of liver cancer and cirrhosis caused by hepatitis
C is likely to continue to grow in the United States despite curative treatment
for hepatitis C, and people who have cirrhosis ...
- Liz Highleyman | 16 November 2015
An 8-week triple combination of Gilead Sciences'
sofosbuvir, velpatasvir and GS-9857 showed a high sustained response rate in a
phase 2 study of people with difficult-to-treat hepatitis C virus (HCV),
including treatment-experienced people ...