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Standard TB tests may not detect infection in certain exposed individuals

An international collaboration of infectious disease experts has identified a large group of people who appear to have naturally mounted an immune response to TB, a bacterial infection that is the leading cause of infectious disease death worldwide. Nearly 200 people from 2500 households with active TB were clearly exposed to TB for more than 10 years but the two most reliable tests (TST and IGRA) came back negative on repeated tests.

Published
02 July 2019
From
EurekAlert
Novel point-of-care TB test for patients with HIV superior to current test

Study findings showed that a novel point-of-care tuberculosis test for patients with HIV offers superior diagnostic sensitivity to the currently available test while maintaining specificity, researchers reported.

Published
12 June 2019
From
Healio
Xpert Ultra test for diagnosing TB now included in Cochrane Review

The review author team found Xpert MTB/RIF to be sensitive and specific for diagnosing pulmonary TB and rifampicin resistance, consistent with findings reported previously. Compared with Xpert MTB/RIF, Xpert Ultra had higher sensitivity and lower specificity for TB detection and similar sensitivity and specificity for rifampicin resistance detection (one study).

Published
11 June 2019
From
EurekAlert
Xpert testing to find TB in people with advanced HIV at diagnosis saves lives, study finds

A study reported in Clinical Infectious Diseases this week confirms that patients newly diagnosed with HIV who were screened for TB with Xpert technology had higher survival rates in the year that followed than those screened with a point-of-care test using flourescent light-emitting microscopy.

Published
08 April 2019
From
Science Speaks
Urine testing of people with HIV for tuberculosis can save lives and be cost-effective

Screening all hospitalized patients with HIV for tuberculosis using urine tests would improve life expectancy and be cost-effective in Malawi and South Africa, reports an international team of investigators led by Massachusetts General Hospital physicians.

Published
23 January 2019
From
Eurekalert Inf Dis
Fast, Cheap Testing for Tuberculosis? Soon It May Be Possible

Diagnosing a lung disease like tuberculosis with a urine test may seem illogical, but a group of American researchers is now a step closer to that goal. Scientists at George Mason University have improved by at least 100 times the accuracy of testing for a sugar shed by tuberculosis bacteria, meaning that a simple dipstick urine test may soon become possible.

Published
02 January 2018
From
New York Times
3 innovations that could transform TB diagnosis and care

Ending global tuberculosis will require new diagnostic tools, new ways to support adherence to treatment, new drug regimens, and a vaccine, experts told Devex at the 48th Union World Conference on Lung Health.

Published
18 October 2017
From
Devex
TB/HIV outreach finding patients in remote South Africa

A novel tuberculosis and HIV case-finding method effectively detected people with both diseases in a remote area of South Africa, according to researchers.

Published
10 May 2017
From
Healio
‘Significant success’ in reducing TB and HIV/Aids in SA’s prisons

Data presented at a five-day stakeholder meeting shows ‘significant success in screening and treatment for tuberculosis in Free State, Northern Cape and KwaZulu-Natal prisons.

Published
16 March 2017
From
Medical Brief
IDSA Guidelines Recommend Newer Tests to Diagnose Tuberculosis

Patients at risk for latent or active tuberculosis (TB) infection should be assessed with newer tests, including interferon-gamma release assays (IGRAs) and molecular diagnostics, recommend guidelines on TB diagnosis developed by the American Thoracic Society (ATS), Infectious Diseases Society of America (IDSA) and Centers for Disease Control and Prevention (CDC) and published in the journal Clinical Infectious Diseases. Advances in testing prompted the first new guidelines on TB diagnosis in 17 years.

Published
19 December 2016
From
IDSA
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.