Hepatitis and HIV

Hepatitis and HIV features

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  EASL issues new hepatitis C treatment recommendations for all genotypes

  The European Association for the Study of the Liver (EASL) released its latest recommendations on treatment of hepatitis C at a special meeting last Thursday in Paris....

  From:  News

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  Staying free of hepatitis C

  It's still not clear exactly how HIV-positive gay men are contracting hepatitis C through sex. Until we know with certainty, Derek Thaczuk asks, how can we avoid co-infection?...

  From:  HIV treatment update

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  Combinations and conundrums: the challenges of hepatitis C treatment

  A multiplicity of new drugs for hepatitis C are being researched. As Gus Cairns discovers, though, they face an elusive enemy, a shape-shifter of a virus that won’t...

  From:  HIV treatment update

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  The new epidemic: HIV and hepatitis C infection in gay men

  “I’m surprised there isn’t a greater sense of urgency about this in the community.” Those were the words of Dr Kevin Fenton of the US Centers for...

  From:  HIV treatment update

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  Double trouble – how hepatitis C is on the increase in HIV-positive gay men

  Studies at CROI showed how hepatitis C is gaining ground, says Gus Cairns. ...

  From:  HIV treatment update

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  Management of HIV and hepatitis B or C co-infection in resource-limited settings

  Review of management of HIV and hepatitis co-infection with particular focus on antiretroviral therapy and liver disease in resource-limited settings....

  From:  HIV & AIDS treatment in practice

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  HIV and hepatitis in non-injecting drug users

  Management of HIV and hepatitis in non-injecting drug users in resource-limited settings....

  From:  HIV & AIDS treatment in practice

Hepatitis and HIV in your own words

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  Living with HIV and hep C co-infection and haemophilia

  For most people, coping with HIV is enough of a problem in itself, but when you throw in a lifetime disorder such as haemophilia, and...

  From: In your own words

Hepatitis and HIV news from aidsmap

• Hepatitis C does not raise risk of heart disease or cancers in people with HIV

  Hepatitis C coinfection does not increase the risk of cardiovascular disease or non-AIDS cancers in people with HIV, an analysis of the large Eurosida cohort published in Clinical Infectious Diseases has found. Although the long-term impact of hepatitis ...

  19 July 2019 | Keith Alcorn

• Just 18% of people with hepatitis/HIV co-infection and cirrhosis are screened for liver cancer as often as recommended

  There is a “strikingly low adherence” to clinical guidelines for ultrasound screening for hepatocellular carcinoma in western Europe, researchers report in the Journal of Viral Hepatitis.Over years or decades, chronic hepatitis B or C can cause serious liver disease ...

  10 June 2019 | Roger Pebody

• Hepatitis C more stigmatising than HIV: gay men’s attitudes towards hepatitis C reinfection

  Qualitative research with HIV-positive gay and bisexual men in Australia who had been cured of hepatitis C infection revealed that having hepatitis C was more stigmatising than HIV infection. While being a member of certain social and sexual networks ...

  04 June 2019 | Krishen Samuel

• Fatty liver disease a rising cause of liver problems in people with HIV

  Now that hepatitis C can be successfully treated, non-alcoholic fatty liver disease (NAFLD) is becoming an increasingly important cause of serious liver problems and liver-related death among people living with HIV in the US, according to a report at the ...

  24 April 2019 | Liz Highleyman

• EACS Standard of Care meeting report – Tackling HIV and co-infections in Europe: towards common standards

  This is the full report from the EACS Standard of Care Meeting. It can also be read in three separate sections here.Eastern Europe continues to have one of the few HIV epidemics in the world where HIV incidence ...

  29 March 2019 | Gus Cairns

• Epidemic of sexually transmitted hepatitis C in gay men now involves both HIV-positive and HIV-negative men

  Incidence of acute hepatitis C virus (HCV) among men who have sex with men (MSM) who use pre-exposure prophylaxis (PrEP) in Lyon increased tenfold between 2016 and 2017, according to research published in Clinical Infectious Diseases. ...

  29 March 2019 | Michael Carter

• Higher HIV viral load and lower CD4 count linked to liver cancer risk

  People living with HIV who have a longer duration of detectable viral load and those with low CD4 cell counts have a higher likelihood of developing liver cancer in the absence of advanced fibrosis, according to a study presented ...

  13 March 2019 | Liz Highleyman

• Sixfold increased risk of infant HIV infection and high rates of low birth weight among women with HIV/hepatitis B co-infection

  Women with high levels of hepatitis B viraemia (>106IU/ml) who have co-infection with HIV had a more than sixfold increased risk of having infants with HIV infection compared to women with HIV alone or co-infected with low levels of ...

  12 March 2019 | Carole Leach-Lemens

• EACS takes steps towards a common, auditable European standard of care

  The purpose of the European AIDS Clinical Society's (EACS) meeting in January in Bucharest, Romania was to devise consistent, auditable standards of care for HIV, co-infection and co-morbidity treatment throughout Europe. See this report and this report for ...

  11 March 2019 | Gus Cairns

• Hepatitis C drops among HIV-positive London gay men after direct-acting antiviral scale-up

  New cases of hepatitis C virus (HCV) infection among HIV-positive gay and bisexual men seen at three clinics in London have declined by nearly 70% since 2015, according to a presentation yesterday at the Conference on Retroviruses and Opportunistic ...

  07 March 2019 | Liz Highleyman

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Hepatitis and HIV news selected from other sources

• Preventing Drug Induced Liver Injury in Patients with HIV

  With an estimated annual incidence rate of 13.9 to 24 per 100,000 inhabitants, drug-induced liver injury (DILI) the leading cause of acute liver failure in the United States. It is also a unique concern in people living with HIV. Recognizing the importance of comorbid HIV and DILI, researchers from Sacco University Hospital in Milano, Italy, have published a comprehensive review of the topic ahead-of-print in the journal Pharmacological Research.

  03 June 2019 | Pharmacy Times

• Hepatic Steatosis Highly Prevalent in Young Adults With Lifelong HIV

  One-third of young adults living with HIV since birth or early childhood have hepatic steatosis.

  17 April 2019 | Infectious Disease Advisor

• Summary from CROI 2019 for viral Hepatitis, from Jürgen Rockstroh

  Although no new drugs for HBV or HCV therapy were presented a whole range of important clinical studies were discussed which all have important clinical implications for daily practice.

  09 April 2019 | NATAP

• Hepatitis C deaths fall by 16 per cent between 2015 and 2017

  Deaths from serious hepatitis C related liver disease fell by 16.1% between 2015 and 2017 according to data from PHE.

  09 April 2019 | Public Health England

• Hepatic steatosis common in young adults with life-long HIV

  Thirty-three percent of young adults with HIV since birth or early childhood have hepatic steatosis, a prevalence comparable to older adults with HIV and “significantly higher” than HIV-negative controls, according to research published in The Journal of Infectious Diseases

  26 March 2019 | Healio

• Expert working group recommends bold action to eliminate hepatitis C in Scotland; now we need a national elimination strategy

  A new report published by Health Protection Scotland sets out national recommendations for improvements to case finding and access to care which would accelerate Scotland’s efforts to eliminate hepatitis C. The Hepatitis C Trust calls on the Scottish Government to set out a clear timeline and process for developing and releasing a national elimination strategy for hepatitis C, in order to facilitate implementation of the recommendations contained in the recent Health Protection Scotland report.

  19 February 2019 | Hepatitis C Trust

• Trial launched to study HIV-to-HIV liver transplant outcomes

  The new study will track the success of 80 liver transplants to HIV-positive people. Half of the livers will come from deceased HIV-positive donors and the other half will come from deceased HIV-negative donors.

  16 February 2019 | UPI

• Low testosterone persists after HCV clearance

  Low levels of free testosterone are common among men with chronic hepatitis C infection following SVR and persist after HCV clearance, according to findings from a prospective, longitudinal cohort study.

  12 February 2019 | Healio

• England: Countdown to hep C eradication

  NHS England’s target date to eliminate hepatitis C is now just six years away. DDN hears what progress has been made, and what’s left to achieve, at the LJWG on Substance Use and Hepatitis C annual conference.

  05 February 2019 | Drink & Drug News

• UK court dismisses AbbVie's legal challenge against the NHS

  The High Court has dismissed a legal challenge by US pharmaceutical firm AbbVie against the National Health Service (NHS) England's procurement deal for drugs to treat and cure hepatitis C. The decision means that the plan to eliminate the virus in England remains on track.

  25 January 2019 | The Lancet (free registration required)

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