Kidney toxicity

The kidneys are two organs that sit in the small of the back on either side of the spinal cord. The kidneys filter toxic substances from the blood; help balance fluid, acid, and electrolyte levels; and reabsorb water and nutrients back into the body. The kidneys produce urine from excess water and waste products, which is stored in the bladder until eliminated. Because the kidneys filter toxic substances, including some drugs, they are susceptible to damage if these substances build up in the proximal tubules, the site where reabsorption of excess water takes place.

Some anti-HIV drugs have been linked to kidney toxicity, particularly tenofovir (Viread) and indinavir (Crixivan). HIV infection is itself associated with kidney impairment, especially in later stages of disease.

Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap

This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.