Nicotinic acid (niacin)

Nicotinic acid is also known as vitamin B3 or niacin. In the human body niacin plays a role in fat synthesis, protein and carbohydrate breakdown, tissue respiration and digestion.

As a high-dose supplement, niacin is effective at lowering both cholesterol and triglycerides in people taking antiretroviral therapy, but its use is limited due to side-effects including dilation of the veins, headache, flushing, dizziness, palpitations, nausea, and insulin resistance. 1 A second member of this group, acipimox (Olbetam), has fewer side-effects but is less effective at reducing lipids.

References

  1. Gerber M et al. Niacin in HIV-infected individuals with hyperlipidemia receiving potent antiretroviral therapy. Tenth Conference on Retroviruses and Opportunistic Infections, Boston, abstract P726, 2003
Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.