Treatment outcomes and life expectancy

Treatment outcomes and life expectancy features

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  START trial finds that early treatment improves outcomes for people with HIV

  A major international randomised clinical trial has found that people living with HIV have a considerably lower risk of developing AIDS or other serious illnesses...

  From:  News

• No improvements in CD4 count at diagnosis in African patients in last decade

  A study by Harvard Medical School has found that the average CD4 count in sub-Saharan African people who are diagnosed with HIV has not risen since 2002....

  From:  News

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  How much longer have I got?

  We’re concentrating on the future as a theme in this, the last-ever HIV treatment update. So it seems appropriate to have an update on exactly how much...

  From:  HIV treatment update

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  How long have I got, doc?

  Can people with HIV really live as long as anyone else? Gus Cairns investigates ...

  From:  HIV treatment update

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  Why we won’t die of AIDS

  A study in France has found that, whatever older people with HIV die of, it probably won’t be AIDS. In recent years one of the increasingly hot topics...

  From:  HIV treatment update

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  How does HIV make us sick?

  Nearly 30 years after the first documented cases of AIDS, we still don’t know exactly how HIV destroys the immune system. But inflammation – sustained immune activation...

  From:  HIV treatment update

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  Adherence and long-term treatment success

  Taking your HIV medication correctly (the technical term for this is adherence) is the single most important thing you can do to make sure your HIV treatment...

  From:  HIV treatment update

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  A ‘functional cure’?

  Examining the excitement over a bone marrow transplant that ‘eradicated’ HIV, by Edwin J Bernard. ...

  From:  HIV treatment update

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  Can we create ‘elite controllers’?

  Is combination immunotherapy the future? ask Edwin J Bernard and Derek Thaczuk ...

  From:  HIV treatment update

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  Defining, and then watching for, treatment failure

  A review of various clinical, immunological and virological definitions of antiretroviral treatment failure in resource-limited settings....

  From:  HIV & AIDS treatment in practice

Treatment outcomes and life expectancy in your own words

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  Life on HIV treatment – a personal perspective

  I’ve been taking HIV treatment for ten years – that's longer than the average life expectancy of someone with HIV when I was diagnosed back in 1991. I’ve...

  From: In your own words

Treatment outcomes and life expectancy news from aidsmap

• Opioid overdose deaths are rising among people with HIV in the United States

  A growing number of people with HIV in the US are dying from opioid overdoses, according to a presentation at the Conference on Retroviruses and Opportunistic Infections (CROI 2019) this month in Seattle. While total mortality among HIV-positive ...

  28 March 2019 | Liz Highleyman

• Multiple benefits to scaling up universal test and treat in Africa

  As well as the important findings of PopART, the largest HIV prevention trial ever conducted, this week’s Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle heard about several other studies from African countries which have scaled up universal testing ...

  08 March 2019 | Roger Pebody

• DAA treatment reduces the risk of death and liver cancer in people with hepatitis C

  Treatment with direct-acting antivirals (DAAs) reduced the risk of death, liver cancer and death from liver-related causes in French people with hepatitis C, according to results of one of the largest studies to date of the ...

  13 February 2019 | Keith Alcorn

• Glimmers of hope: moving towards better HIV and TB treatment in eastern Europe

  Eastern Europe continues to have one of the worst HIV epidemics in the world outside sub-Saharan Africa, with the worst linkage to care of any region in the world, last week's meeting on Standard of Care for HIV ...

  07 February 2019 | Gus Cairns

• Is ageing in people living with HIV accelerated or accentuated?

  Earlier than normal ageing in people living with HIV has been debated for many years. The issue emerged when it became clear that HIV-positive people had an increased burden of cardiovascular disease, cancer and other diseases that are associated ...

  30 January 2019 | Alain Volny-Anne

• Atripla or efavirenz plus Truvada failed one in 16 people in first year

  Although analyses of the failure rate of ART have been conducted before, a new analysis is the first to compute these rates for a single-drug regimen – namely efavirenz, tenofovir and emtricitabine, the one used most frequently in ...

  21 January 2019 | Gus Cairns

• HIV treatment outcomes continue to get better, says large analysis

  The efficacy of first-line antiretroviral therapy (ART) continues to improve, according to an analysis of outcomes in 78,000 people in 181 studies, published in AIDS by Professor Andrew Carr of St Vincent's Hospital in Sydney and colleagues. Over ...

  27 December 2018 | Michael Carter

• CD4 count recovery: French study reaffirms why it is important to test and treat HIV early

  Seven-in-ten people with HIV taking combined antiretroviral therapy for the first time recover their CD4 cell count to above 500 cells/mm3, French researchers report in AIDS. Having a higher CD4 cell count and a higher CD4/CD8 ratio at the ...

  03 December 2018 | Alain Volny-Anne

• HIV diagnoses fell in the UK in 2017 for the first time among all risk groups, all ethnicities and in all regions, annual report reveals

  The 2018 report from Public Health England is entitled Progress towards ending the HIV epidemic in the United Kingdom, and for once the note of optimism in the title is justified.The report describes an epidemic in which new ...

  29 November 2018 | Gus Cairns

• People living with HIV underestimate the harm of smoking

  People with HIV in Denmark who smoke greatly underestimate the impact of smoking on life expectancy, a study of perceptions of life expectancy published this month in the Journal of Acquired Immune Deficiency Syndromes shows. Current smokers living with HIV, ...

  03 October 2018 | Keith Alcorn

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Treatment outcomes and life expectancy news selected from other sources

• Once Engaged in Care, Trans Women Have High Rates of HIV Suppression

  Continuum of care review finds 80% of transgender women in care achieve an undetectable viral load.

  01 July 2019 | POZ

• Many Women on HIV Treatment Are at Risk of Developing a Detectable Viral Load

  An ongoing study finds that considerable challenges in such women’s lives may compromise their adherence to antiretrovirals.

  22 May 2019 | Poz

• More than 1 year to HIV control raises failure risk almost 10-fold

  Failure to reach an undetectable viral load in the first year of antiretroviral therapy (ART) led to nearly a 10-fold higher risk of subsequent virologic failure in a 17,000-person North American analysis [1]. Taking more than 1 year to control HIV did not confer a higher risk of low-level viremia or viral blips in this 6-year study.

  15 March 2019 | NATAP

• Up to 95% virologic response rate with rapid ART in safety-net clinic

  Up to 95% of people with newly diagnosed HIV and beginning antiretroviral therapy (ART) within a week of diagnosis reached a viral load below 50 copies in the first year of therapy. High proportions of people in this San Francisco safety-net clinic had a substance use disorder, a major mental health diagnosis, or unstable housing.

  14 March 2019 | NATAP

• Wider ART Rollout Tied to Declines in HIV Mortality in Kenya

  Both all-cause mortality and mortality among HIV-positive people dropped in Western Kenya following a scale-up of antiretroviral therapy (ART), a researcher said here. From 2011 to 2016, all-cause mortality dropped from 10.0 per 1,000 person years (95% CI 8.4-11.7) to 7.5 per 1,000 person years (95% CI 5.8-9.1), reported Emily C. Zielinski-Gutierrez, DrPH, of the CDC.

  12 March 2019 | MedPage Today

• Uganda: Financial incentives do not boost HIV viral suppression rate

  Financial incentives had no effect on viral suppression among HIV-positive adults in Uganda, according to a recent study. Researchers said these findings suggest a need for better interventions to promote the achievement of viral suppression.

  25 January 2019 | Healio

• The Lisbon Patient: Meet the man living with HIV who's about to turn 100

  Referred to in a soon-to-be published case study as “The Lisbon Patient,” Miguel -- which is not his real name -- is also the oldest documented person with HIV in the world.

  18 December 2018 | CTV

• Kenya: Riddle of gender disparities in HIV-Aids deaths

  Why are men more likely to die from HIV compared with women?

  01 December 2018 | Daily Nation

• Navigating Mixed Messages About HIV

  We are required to both downplay the seriousness of HIV and to stress its terrible impact. Here’s the view I favor.

  08 June 2018 | Poz

• Starting HIV treatment at diagnosis slashes drop out, drug failure rates, China study finds

  Patients diagnosed with HIV who started antiretroviral treatment within 30 days had significantly lower rates of dropping out of treatment, and higher rates successful treatment, than those who started later, particularly those who started more than three months after their diagnosis, a study in China has found.

  04 June 2018 | Science Speaks

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