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How HIV works
HIV’s genetic code, extracted from a nub of tissue, adds to evidence of virus’ emergence in humans a century ago

Scientists at the University of Arizona examined a tissue sample that dates back to the 1960s, the oldest sample of HIV to date, and concluded the virus jumped from primates earlier than expected.

Published
17 July 2019
From
STAT
Neurological and cognitive problems
HIV May Persist in the Brain Despite Antiretroviral Treatment

After almost a decade on antiretroviral therapy, half of study participants still had HIV in immune cells in their brain and spinal fluid.

Published
17 July 2019
From
Poz
The search for a cure
Have mice really been cured of HIV using CRISPR gene editing?

The claim is they have eliminated HIV from living animals for the first time, by cutting it out of its hiding places in the body – in other words, that they have cured the animals.

Published
03 July 2019
From
New Scientist
How HIV works
HIV eliminated from the genomes of living animals

In a major collaborative effort, researchers at the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) have for the first time eliminated replication-competent HIV-1 DNA -- the virus responsible for AIDS -- from the genomes of living animals. The study, reported online July 2 in the journal Nature Communications, marks a critical step toward the development of a possible cure for human HIV infection.

Published
03 July 2019
From
Eurekalert Inf Dis
The search for a cure
Is It Safe to Alter the CCR5 Receptor? And How Will This Influence HIV Cure Studies?

The HIV cure effort suffered a potential setback this week, as researchers reported an association between having two copies of the CCR5-∆32 mutation and shorter survival.

Published
11 June 2019
From
NEJM Journal Watch
How HIV works
Early antiretroviral treatment may preserve key immune responses to HIV

Investigators from the Ragon Institute of MGH, MIT and Harvard have found that instituting combination antiretroviral treatment at the earliest stages of HIV infection may allow the generation of functional CD8 'killer' T cells and preservation of the CD4 helper T cells that are the virus's primary target.

Published
23 May 2019
From
Eurekalert Inf Dis
How HIV works
Scientists Identify Factors That Make People Naturally Resistant to HIV

Studying key points on the HIV virus that are weak to immune system attacks could lead to new treatments or HIV vaccines.

Published
07 May 2019
From
Smithsonian
How HIV works
In rare cases, immune system fails despite HIV suppression

Antiretroviral therapy (ART) is usually effective at suppressing HIV, allowing the immune system to recover by preventing the virus from destroying CD4+ T cells. Scientists have now identified a rare, paradoxical response to ART called extreme immune decline, or EXID. Five individuals evaluated at the NIAID experienced a significant decline in CD4+ T cell levels despite suppression of HIV below detectable levels for more than three years, according to a new report.

Published
23 April 2019
From
EurekAlert
How HIV works
New study reveals HIV’s vulnerabilities, opening up possibilities for complementary therapies

A new study’s findings suggest that we may have found a way to reveal the virus’s presence in human cells. In the study published Wednesday in Cell & Host Microbe, scientists were able to identify a new shape of an essential HIV protein that allows the virus to gain entry into our cells. And it turns out that keeping this protein — known as Envelope — in this new shape might reveal vulnerabilities within the virus to make it visible to the immune system.

Published
11 April 2019
From
STAT
The biology of HIV transmission
Your sexual partners can change your microbiome, finds a study in mice

The study also hints at a link between those microbiome changes and a person's immune system and susceptibility to infections like HIV.

Published
05 April 2019
From
STAT
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.