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Standard TB tests may not detect infection in certain exposed individuals

An international collaboration of infectious disease experts has identified a large group of people who appear to have naturally mounted an immune response to TB, a bacterial infection that is the leading cause of infectious disease death worldwide. Nearly 200 people from 2500 households with active TB were clearly exposed to TB for more than 10 years but the two most reliable tests (TST and IGRA) came back negative on repeated tests.

Published
02 July 2019
From
EurekAlert
Novel point-of-care TB test for patients with HIV superior to current test

Study findings showed that a novel point-of-care tuberculosis test for patients with HIV offers superior diagnostic sensitivity to the currently available test while maintaining specificity, researchers reported.

Published
12 June 2019
From
Healio
Xpert Ultra test for diagnosing TB now included in Cochrane Review

The review author team found Xpert MTB/RIF to be sensitive and specific for diagnosing pulmonary TB and rifampicin resistance, consistent with findings reported previously. Compared with Xpert MTB/RIF, Xpert Ultra had higher sensitivity and lower specificity for TB detection and similar sensitivity and specificity for rifampicin resistance detection (one study).

Published
11 June 2019
From
EurekAlert
Malawi: ART alone isn't enough to stop the TB epidemic among people with HIV

Expanded access to antiretroviral therapy (ART) has been accompanied by big falls in incidence of tuberculosis (TB) in Malawi, according to research published in the Journal of the

Published
27 May 2019
By
Michael Carter
TB LAM test improves TB diagnosis in people with low CD4 counts

Use of the TB LAM test in people with HIV with CD4 counts below 200 boosted the number of people diagnosed with tuberculosis (TB) by a third,

Published
21 May 2019
By
Keith Alcorn
Xpert testing to find TB in people with advanced HIV at diagnosis saves lives, study finds

A study reported in Clinical Infectious Diseases this week confirms that patients newly diagnosed with HIV who were screened for TB with Xpert technology had higher survival rates in the year that followed than those screened with a point-of-care test using flourescent light-emitting microscopy.

Published
08 April 2019
From
Science Speaks
Glimmers of hope: moving towards better HIV and TB treatment in eastern Europe

Eastern Europe continues to have one of the worst HIV epidemics in the world outside sub-Saharan Africa, with the worst linkage to care of any region in

Published
07 February 2019
By
Gus Cairns
Urine testing of people with HIV for tuberculosis can save lives and be cost-effective

Screening all hospitalized patients with HIV for tuberculosis using urine tests would improve life expectancy and be cost-effective in Malawi and South Africa, reports an international team of investigators led by Massachusetts General Hospital physicians.

Published
23 January 2019
From
Eurekalert Inf Dis
TB symptom screen less likely to detect active TB in people taking HIV treatment

The four-symptom screen for active tuberculosis (TB) that is recommended for all people living with HIV in lower-income settings is less likely to detect active TB in

Published
14 September 2018
By
Keith Alcorn
New TB cases occur rapidly among close contacts of people with pulmonary TB

The close contacts of people with active pulmonary tuberculosis (TB) have high rates of the disease, according to US and Canadian research published in The

Published
12 June 2018
By
Michael Carter
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.