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Search through all our worldwide HIV and AIDS news and features, using the topics below to filter your results by subjects including HIV treatment, transmission and prevention, and hepatitis and TB co-infections.

Tuberculosis and HIV news

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TB treatment
Will a new TB treatment be available soon?

Experts advising the U.S. Food and Drug Administration on marketed and investigational drugs for infectious diseases and disorders were divided on whether the regulatory agency should approve a new drug as part of a proposed combination therapy for highly resistant tuberculosis. The majority of the independent experts — 14 out of 18 — advising the regulatory agency voted favorably last month. But the remaining four found insufficient evidence on efficacy and safety of the TB Alliance’s oral anti-TB drug pretomanid when used in combination with bedaquiline and linezolid, or BPaL.

Published
08 July 2019
From
Devex
TB transmission and prevention
Uganda Launches Scale-up Plan for Tuberculosis Preventive Treatment

The Minister of Health, Dr Jane Ruth Aceng, launched a 100-Day Accelerated Scale-up plan for Tuberculosis Preventive Treatment (TPT) targeting over 300 000 People Living with HIV and AIDS (PLHIV) in Uganda. The government will also provide TPT to all children aged 12 months or more living with HIV as well as HIV-negative infants and children aged 5 years or below who are household contacts of patients with pulmonary Tuberculosis. As part of the scale-up plan, Government will provide TPT at 1 947 Antiretroviral therapy (ART) sites across the country.

Published
08 July 2019
From
World Health Organization
Tuberculosis and HIV
Tuberculosis in SA: Three graphs that tell the story

According to World Health Organization (WHO) estimates, South Africa continues to have one of the highest burdens of tuberculosis (TB) in the world. The burden of a disease refers to the number of infections and deaths within a population and the associated costs of treatment of a specific disease. Here we attempt to tell the story of the burden of TB on human life using several graphs. As the story of TB cannot be separated from that of HIV, we use estimates from both the WHO TB data portal and the Thembisa mathematical model of HIV in South Africa to examine trends in the data from 2000 to 2017.

Published
08 July 2019
From
Spotlight
Tuberculosis and HIV
Major TB reduction impossible without expansion of ART coverage

Tuberculosis incidence in sub-Saharan Africa is falling too slowly to meet global targets of an 80% reduction by 2030, and where incidence is falling, the decline is

Published
08 July 2019
By
Keith Alcorn
TB diagnosis
Standard TB tests may not detect infection in certain exposed individuals

An international collaboration of infectious disease experts has identified a large group of people who appear to have naturally mounted an immune response to TB, a bacterial infection that is the leading cause of infectious disease death worldwide. Nearly 200 people from 2500 households with active TB were clearly exposed to TB for more than 10 years but the two most reliable tests (TST and IGRA) came back negative on repeated tests.

Published
02 July 2019
From
EurekAlert
TB transmission and prevention
NIH launches large TB prevention trial for people exposed to multidrug-resistant TB

A large clinical trial to assess treatments for preventing people at high risk from developing multidrug-resistant tuberculosis (MDR-TB) has begun. The study is comparing the safety and efficacy of a new MDR-TB drug, delamanid, with the decades-old TB drug isoniazid for preventing active MDR-TB disease in children, adolescents and adults at high risk who are exposed to adult household members with MDR-TB.

Published
25 June 2019
From
Eurekalert Medicine & Health
TB diagnosis
Novel point-of-care TB test for patients with HIV superior to current test

Study findings showed that a novel point-of-care tuberculosis test for patients with HIV offers superior diagnostic sensitivity to the currently available test while maintaining specificity, researchers reported.

Published
12 June 2019
From
Healio
TB diagnosis
Xpert Ultra test for diagnosing TB now included in Cochrane Review

The review author team found Xpert MTB/RIF to be sensitive and specific for diagnosing pulmonary TB and rifampicin resistance, consistent with findings reported previously. Compared with Xpert MTB/RIF, Xpert Ultra had higher sensitivity and lower specificity for TB detection and similar sensitivity and specificity for rifampicin resistance detection (one study).

Published
11 June 2019
From
EurekAlert
Drug-resistant TB
FDA Advisory Committee Votes Favorably on the Question of the Effectiveness and Safety of Pretomanid in Combination with Bedaquiline and Linezolid for Treatment of Highly Drug-Resistant Forms of Tuberculosis

Investigational drug pretomanid, developed by non-profit TB Alliance, is under regulatory review for treatment of extensively drug-resistant tuberculosis and treatment-intolerant or non-responsive multidrug-resistant tuberculosis as part of a new investigational regimen that includes bedaquiline and linezolid.

Published
07 June 2019
From
TB Alliance
Tuberculosis and HIV
Malawi: ART alone isn't enough to stop the TB epidemic among people with HIV

Expanded access to antiretroviral therapy (ART) has been accompanied by big falls in incidence of tuberculosis (TB) in Malawi, according to research published in the Journal of the

Published
27 May 2019
By
Michael Carter
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.