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TB CAB statement on safety of using bedaquiline and delamanid together

he Global TB Community Advisory Board (TB CAB) welcomes the important finding from the AIDS Clinical Trials Group Deliberate Trial that newer drugs bedaquiline and delamanid are safe to use together. These findings should erase any remaining reluctance to use these two important drugs together, as the benefits of these safer drugs outweigh the risks--especially for patients with drug-resistant TB who have few other treatment options.

Published
14 March 2019
From
TB Online
Tshepiso study: Preventive TB therapy not associated with poor pregnancy outcomes

Initiating isoniazid preventive therapy for tuberculosis during pregnancy is not associated with a higher rate of poor maternal or infant outcomes, according to observational results from the Tshepiso study presented at CROI.

Published
12 March 2019
From
Healio
Double doses of darunavir given with rifampicin lead to high rates of hepatoxicity

Adjusted doses of darunavir/ritonavir (DRV/r) with rifampicin (RIF) were associated with unacceptable risk of hepatotoxicity and a reduction in DRV trough concentrations in a pharmacokinetic (PK) study, conducted in South Africa, presented at CROI 2019.


Published
12 March 2019
From
HIV i-Base
Co-administration of dolutegravir-based treatment and short course of rifapentine/isoniazid (3HP) well tolerated in people living with HIV

Co-administration of dolutegravir-based antiretroviral therapy and short course (12 weeks) of rifapentine/isoniazid (3HP) for people living with HIV needing preventative treatment for latent tuberculosis (TB) infection was well

Published
12 March 2019
By
Carole Leach-Lemens
EACS takes steps towards a common, auditable European standard of care

The purpose of the European AIDS Clinical Society's (EACS) meeting in January in Bucharest, Romania was to devise consistent, auditable standards of care for HIV, co-infection and

Published
11 March 2019
By
Gus Cairns
TB Preventive Therapy Safe in Pregnant Women

Pregnant women who are infected with HIV and are at risk of tuberculosis co-infection can undergo isoniazid prevention therapy without causing harm to themselves or their babies, researchers suggested here.

Published
08 March 2019
From
MedPage Today
Deadly drug-resistant TB a ‘blinking red’ global threat

“We should all be more worried about multidrug-resistant TB than we are. It gets nothing like the level of attention it should do,” Peter Sands, Global Fund’s head, told AFP during a visit to New Delhi.

Published
07 February 2019
From
South China Morning Post
Vitamin D helps treat lethal drug-resistant TB

Vitamin D has been found to speed up the clearance of tuberculosis (TB) bacteria from the lungs of people with multi-drug resistant TB, according to a study of 1,850 patients receiving antibiotic treatment, led by Queen Mary University of London.

Published
07 February 2019
From
Eurekalert Inf Dis
Glimmers of hope: moving towards better HIV and TB treatment in eastern Europe

Eastern Europe continues to have one of the worst HIV epidemics in the world outside sub-Saharan Africa, with the worst linkage to care of any region in

Published
07 February 2019
By
Gus Cairns
Urine testing of people with HIV for tuberculosis can save lives and be cost-effective

Screening all hospitalized patients with HIV for tuberculosis using urine tests would improve life expectancy and be cost-effective in Malawi and South Africa, reports an international team of investigators led by Massachusetts General Hospital physicians.

Published
23 January 2019
From
Eurekalert Inf Dis

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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.