Massive decline in suicides of HIV-positive people since the introduction of combination therapy, but rate remains high
An analysis of deaths over 30 years in Switzerland shows that suicides fell dramatically after 1996, but have not declined further in men in more recent years as HIV treatment has continued to improve. People with HIV remained three times more likely than people in the general population to die by suicide, according to an analysis of the Swiss HIV Cohort Study report in the Journal of the International AIDS Society.
Statin treatment and physical exercise – including resistance training and cardiovascular workouts – has a range of benefits for HIV-positive people with high blood lipids, according to Brazilian research published in Medicine & Science in Sports & Exercise. Statins and exercise were individually beneficial, but the very best results were seen in individuals who combined the two. Lipids were reduced, as were markers of inflammation associated with an increased risk of cardiovascular disease, while body composition, cardiovascular fitness and muscle strength also improved.
Clusters of new cases of tuberculosis (TB) provide strong evidence of areas that need to be prioritised for improved antiretroviral therapy (ART) coverage, and improved ART coverage is associated with a reduction in new TB cases, according to research carried out in KwaZulu-Natal province, South Africa, published in July in Nature Scientific Reports.
Successful treatment of hepatitis C virus (HCV) may lead to a reduction in immune activation related to leakage of bacteria from the gut in people with HIV/HCV co-infection, according to a study presented at the 10th International AIDS Society Conference on HIV Science (IAS 2019) last month in Mexico City.
HIV diagnoses are going up in gay and bisexual men born in Asia who have recently arrived in Australia, while they are falling in Australian-born men. The disparity may be fuelled by exclusion from government-subsidised healthcare, including HIV treatment and pre-exposure prophylaxis (PrEP), researchers warn.
Being HIV positive is associated with lower sexual function and a higher prevalence of sexual problems, according to research involving middle-aged women conducted in England and published in AIDS Care. Almost twice as many women living with HIV reported low sexual function, with two-thirds of women with HIV also reporting at least one sexual problem in the previous year. Post-menopausal status was associated with sexual dysfunction in women with HIV, an association that was not observed in HIV-negative women.
Dr Asa Radix gave a plenary presentation at the recent 10th International AIDS Society Conference on HIV Science (IAS 2019) in Mexico about the multiple challenges facing transgender people when it comes to preventing HIV infection globally. Radix, a transgender man himself, remarked upon the significance of transgender issues being brought to the fore by being featured on the main stage of this conference for the first time.
Outcomes for some common cancers are significantly poorer among people with HIV over the age of 65 compared to HIV-negative people of the same age, according to research published in JAMA Oncology. The study is especially important because all the patients received appropriate therapy for their cancer soon after it was diagnosed. People with HIV had an increased risk of cancer relapse and death.
The third in an annual series of UK surveys conducted by Public Health England in collaboration with PrEPster and iwantPrEPnow reports that although the proportion of people who have ever used HIV pre-exposure prophylaxis (PrEP) has not increased since the previous survey, a higher proportion report currently using PrEP.
Some HIV-positive people with extensive experience of antiretroviral therapy (ART), drug resistance and few treatment options need intensive adherence support in order to suppress viral load to undetectable levels, according to new US research.