Pre-treatment weight

Many recent studies have indicated that fat accumulation is more common among people who are overweight, or have a high body mass index, before starting therapy; while people with a lower body mass index are more likely to experience fat depletion. 1 2 3 4 Studies have been conflicted as to whether body weight affects the risk of a mixed syndrome of fat accumulation and peripheral fat wasting. 1 4

An Australian prospective study of 40 men found that higher lean body mass at baseline was associated with the development of lipodystrophy. 5

References

  1. Galli M et al. Risk of developing adipose tissue alterations after starting antiretroviral therapy in naive patients. Antivir Ther 5: S59, 2000
  2. Muurahainen N et al. Gender differences in HIV-associated adipose redistribution syndrome (HARS): an update. Seventh Conference on Retroviruses and Opportunistic Infections, San Francisco, abstract 26, 2000a
  3. Muurahainen N et al. Different factors are associated with abnormal fat accumulation and fat depletion in men and women with HIV. Antiviral Therapy 5 (Supp 5): 65, 2000b
  4. Raffi F et al. Substitution of a nonnucleoside reverse transcriptase inhibitor for a protease inhibitor in the treatment of patients with undetectable plasma human immunodeficiency virus type 1 RNA. Clinical Infectious Diseases 31(5): 1274-1278, 2000
  5. Mallon P et al. Prospective evaluation of the effects of antiretroviral therapy on body composition in HIV-1 infected men starting therapy. AIDS 17: 971-979, 2003
Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.