Clindamycin (Dalacin C)

Clindamycin (Dalacin C) is an approved antibiotic that has been investigated as an alternative treatment for toxoplasmosis and Pneumocystis pneumonia (PCP), often in combination with pyrimethamine (Darapim) or primaquine.

Clindamycin is considered to be of limited usefulness because of its potentially serious side-effects, including pseudo-membranous colitis (which can be fatal), diarrhoea, nausea, vomiting, liver impairment, blood abnormalities and rash. However, a recent trial reported that people taking clindamycin experienced fewer side-effects compared with people on standard treatment for PCP.1

Clindamycin is available either in capsule form or as a liquid for intramuscular injection or intravenous infusion. It is usually used in combination with primaquine for PCP and in combination with pyrimethamine for toxoplasmosis.

Clindamycin is manufactured by Pharmacia & Upjohn.


  1. Toma E et al. Clindamycin with primaquine vs. trimethoprim-sulfamethoxazole therapy for mild and moderately severe pneumocystis carinii pneumonia in patients with AIDS: a multicentre, double-blind, randomised trial (CTN 004). Clin Infect Dis 27: 524-530, 1998

Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap

This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

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