Trimethoprim (Monotrim)

Trimethoprim (Monotrim) is an approved antibiotic, which is used most frequently in conjunction with sulfamethoxazole in the form of the drug cotrimoxazole (Septrin). Cotrimoxazole is a first-line therapy for the prevention and treatment of Pneumocystis pneumonia (PCP). Trimethoprim in combination with dapsone is also used for PCP, but with a relatively high rate of allergic skin reactions.

Trimethoprim alone has not been tested against PCP in humans, but studies in rats showed that it was unable to prevent PCP infection whereas the cotrimoxazole combination was successful.

Trimethoprim is available as a generic (non-brand name) product.

Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap

This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.